Facilitating rapid discovery and development of potentially predictive signatures with the most advanced view of immuno-oncology biology.
The PanCancer IO 360 Gene Expression Panel...
nCounter Vantage™ Gene Fusion Panels
nCounter Vantage™ Gene Fusion Panels
Multiplexed Gene Fusion Detection Simplified.
- Save time and sample material with multiplexed gene fusion detection in a single tube.
- Detect rare fusions with highly specific probes designed using patented Junction Sequence design technology.
- Ideal for use with challenging sample types including FFPE tissue.
- Customizable and forward compatible with our growing line of 3D Biology™ products.
nCounter Vantage™ Lung Fusion Panel
The nCounter® Lung Fusion Panel includes 63 probes: 35 for specific fusion detection, 24 for positional gene expression imbalance detection, and 4 internal reference genes.
Specific Lung Gene Fusion Probes detect the following gene fusion families:
| ALK | RET | ROS | NTRK1 |
|---|---|---|---|
| EML4-ALK | CCDC6-RET | CD74-ROS1 | CD74-NTRK1 |
| HIP1-ALK | KIF5B-RET | EZR-ROS1 | MPRIP-NTRK1 |
| KIF5B-ALK | GOPC-ROS1 | ||
| TFG-ALK | LRIG3-ROS1 | ||
| TPR-ALK | SDC4-ROS1 | ||
| SLC34A2-ROS1 | |||
| TPM3-ROS1 |
Lung Imbalance probes detect gene expression imbalance in the following genes:
| ALK | RET | ROS |
|---|---|---|
| 8 probes | 8 probes | 8 probes |
nCounter Vantage™ Leukemia Fusion Panel
The nCounter Vantage Leukemia Fusion Panel includes 42 probes in total: 27 for specific fusion detection, 12 leukemia genes, and 3 internal reference genes.
Leukemia Gene Fusion Probes detect the following gene fusion families:
| CML | ALL | AML | AML/APL |
|---|---|---|---|
| BCR-ABL | E2A-PBX1 | AML-ETO | PML-RARA |
| MLL-AF4 | CBFB-MYH11 | ||
| TEL-AML1 | DEK-NUP214 | ||
| RPN1-EVI1 |
Leukemia Gene Expression Probes:
| Genes for AML, CML and ALL | |||
|---|---|---|---|
| BAALC | ERG | FLT3 | MECOM |
| MLLT11 | MN1 | NRAS | PRAME |
| RB1 | SOCS2 | TP53 | WT1 |
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A Comprehensive Set of Fusion Genes The nCounter Leukemia Fusion Gene Expression Assay Kit allows researchers to profile a comprehensive set of fusion genes which result from balan...
